Solenic Medical, Inc. is a clinical stage company pioneering a non-invasive solution for infected orthopedic implants using Alternating Magnetic Fields (AMF). This technology targets infections complicated by biofilms on implant surfaces. Solenic’s initial focus intends to replace ineffective antibiotic therapies and costly revisional surgeries, currently the standard of care for prosthetic joint infections. This innovative approach addresses a critical unmet need in orthopedics, crucial for an aging population and increased patient volumes undergoing total joint procedures. Additional metallic implant applications have been identified and protected under patent.

The Problem: Implant infections exacerbated by antibiotic-resistant biofilm pose a significant challenge in treatment with enormous annual costs to healthcare providers and payers. Recent publications show rising global infection rates correlated with growing procedural volumes, health comorbidities, lifestyle choices and surgical care. Prosthetic joint infections are the primary indication for revision arthroplasty, accounting for up to 10% of all amputations and mortality rates equal to or higher than some common cancers. Current treatment protocols incorporating antibiotics, surgical debridement, and surgical revisions continue to have high failure rates in resolving these debilitating infections with direct and indirect healthcare costs averaging $400,000 per incident.

The Solution: Solenic offers a non-invasive thermal approach for eliminating biofilm from prosthetic joints using AMF, thereby allowing antibiotics and the body’s immune system to clear an infection. In-vitro and large animal studies demonstrated significant efficacy within safe temperature ranges. The scientifically incorporated simulations for individual manufacturer implants, including geometry and composition, continue to receive positive feedback and inclusion from regulatory bodies.

Market Opportunity: Infections are a major concern for all orthopedic surgeries with metallic implants. The orthopedic market, comprising orthopedic implants and fixation devices for fractures is reported at $60B and projected to reach $80B by 2030. Joint replacement and orthopedic implants account for $25B and are projected to grow to $37B by 2035. The global spinal implant and devices market was valued at $21.4 billion in 2024 and is projected to grow to $32 billion by 2029. Additionally, metal implants in cardiology and dentistry offer promising future applications.